Health authorities and medical professionals across India have renewed warnings about the risks posed by the improper use of common pain-relief medicines. The debate gained visibility after recent public remarks by Prime Minister Narendra Modi, who highlighted wider concerns about drug misuse and the growing threat of resistance to certain medicines.
Physicians say that while painkillers play a vital role in treating pain and saving lives, their overuse or unsupervised use can cause serious and sometimes life-threatening side effects. The issue has attracted attention not only from clinicians but also from policymakers and patient groups, particularly given the widespread availability of many analgesics over the counter.
Painkiller side effects: what doctors are warning about
Medical experts point to several important risks associated with commonly used painkillers. Acetaminophen, widely used for fever and pain, can cause severe liver damage if taken in excess. Non-steroidal anti-inflammatory drugs, or NSAIDs, are linked to kidney injury and increased risk of gastrointestinal bleeding, especially when combined with alcohol or when taken by people with pre-existing health conditions.
Doctors also caution about medication interactions. Patients taking multiple prescriptions or substances may unknowingly increase their risk of adverse reactions. Older adults and people with chronic illnesses face higher risks and should avoid self-prescribing without clinical oversight.
Beyond individual harm, the medical community is concerned about a broader culture of self-medication. Prime Minister Modi’s remarks during a recent national address drew attention to the misuse of antibiotics and the growing problem of antibiotic resistance. Although antibiotics differ from painkillers, the concern reflects a shared problem: unsupervised access to medication can produce public health consequences.
Clinicians and pharmacists are urging several measures. Patients should seek medical advice for persistent pain rather than relying on repeated or escalating doses of over-the-counter analgesics. Healthcare providers recommend reading dosage instructions carefully and avoiding mixing different painkillers unless directed. Pharmacists can play a key role in screening for risky combinations and advising patients on safer alternatives or referral to a physician where necessary.
Public health advocates are calling for clearer labelling, better public education and, where appropriate, regulatory changes to restrict easy access to higher-risk formulations. Some hospitals and professional bodies are also working on targeted campaigns to inform older adults and caregivers about the safe use of pain medication.
While specific drug names have featured in public debate, authorities stress that the central message is caution and consultation. Pain-relief medicines are effective when used correctly but can be harmful when misused. Clinicians recommend that people experiencing chronic or severe pain should consult a doctor to establish an appropriate diagnosis and treatment plan, which may include non-drug therapies or specialist referral.
In the short term, experts expect renewed public messaging and greater engagement from primary care providers to reduce harm. Longer term, they hope for a cultural shift away from self-medication and towards informed, supervised use of medicines. For now, doctors advise that anyone taking regular medication review their regimen with a healthcare professional to ensure safe and effective treatment.
Key Takeaways:
- Doctors in India warn that improper use of over-the-counter painkillers can cause serious harm, prompting renewed public health alerts.
- Painkiller side effects include risks to the liver, kidneys and gastrointestinal system when taken without medical advice.
- Prime Minister Narendra Modi and health professionals have raised concerns about medicine misuse and antibiotic resistance.
- Experts urge patients to consult physicians before using analgesics and to limit self-medication.

















